# Copyright © 1996-2007 SRI International, Marine Biological Laboratory, DoubleTwist Inc., The Institute for Genomic Research, J. Craig Venter Institute, University of California at San Diego, and UNAM. All Rights Reserved. # # # Please see the license agreement regarding the use of and distribution of this file. # The format of this file is defined at http://bioinformatics.ai.sri.com/ptools/flatfile-format.html . # # Species: E. coli K-12 # Database: EcoCyc # Version: 11.5 # File Name: enzrxns.dat # Date and time generated: August 6, 2007, 17:31:13 # # Attributes: # UNIQUE-ID # TYPES # COMMON-NAME # ACTIVATORS-ALLOSTERIC # ACTIVATORS-NONALLOSTERIC # ACTIVATORS-UNKMECH # ALTERNATIVE-COFACTORS # ALTERNATIVE-SUBSTRATES # BASIS-FOR-ASSIGNMENT # CITATIONS # COFACTOR-BINDING-COMMENT # COFACTORS # COFACTORS-OR-PROSTHETIC-GROUPS # COMMENT # CREDITS # DATA-SOURCE # DBLINKS # ENZYME # INHIBITORS-ALLOSTERIC # INHIBITORS-COMPETITIVE # INHIBITORS-IRREVERSIBLE # INHIBITORS-NONCOMPETITIVE # INHIBITORS-OTHER # INHIBITORS-UNCOMPETITIVE # INHIBITORS-UNKMECH # INSTANCE-NAME-TEMPLATE # KM # PH-OPT # PHYSIOLOGICALLY-RELEVANT # PROSTHETIC-GROUPS # REACTION # REACTION-DIRECTION # REGULATED-BY # REQUIRED-PROTEIN-COMPLEX # SYNONYMS # TEMPERATURE-OPT # UNIQUE-ID - XYLULOKIN-ENZRXN TYPES - Enzymatic-Reactions COMMON-NAME - xylulokinase CITATIONS - 17123542:EV-EXP-IDA-PURIFIED-PROTEIN:3377353002:keseler CITATIONS - 14597191:EV-EXP-IDA-PURIFIED-PROTEIN:3377360280:keseler COMMENT - D-xylulose is strongly preferred over alternative substrates; the catalytic efficiency with substrates such as /D-ribulose and D-arabitol is 50- to 1300-fold lower |CITS: [17123542]|. ENZYME - CPLX0-7466 KM - (D-XYLULOSE 290) REACTION - XYLULOKIN-RXN REACTION-DIRECTION - PHYSIOL-LEFT-TO-RIGHT REGULATED-BY - REG0-7094 REGULATED-BY - REG0-7093 SYNONYMS - xylulose kinase // UNIQUE-ID - XYLISOM-ENZRXN TYPES - Enzymatic-Reactions COMMON-NAME - xylose isomerase ALTERNATIVE-SUBSTRATES - (XYLOSE GLC) CITATIONS - 6344793:EV-EXP-IDA-UNPURIFIED-PROTEIN:3377366762:keseler CITATIONS - 6327696:EV-EXP-IDA-PART-PURIFIED-PROTEIN:3377366762:keseler CITATIONS - 2405386:EV-EXP-IDA-PART-PURIFIED-PROTEIN:3377366762:keseler COFACTORS - MN+2 COMMENT - The enzyme is also able to convert D-glucose to D-fructose under certain non-physiological conditions; the /KM for glucose is 0.5 M |CITS: [6344793]|. ENZYME - XYLISOM-CPLX KM - (XYLOSE 10000) REACTION - XYLISOM-RXN REACTION-DIRECTION - REVERSIBLE SYNONYMS - D-xylose ketol-isomerase // UNIQUE-ID - XANTHOSINEPHOSPHORY-ENZRXN TYPES - Enzymatic-Reactions COMMON-NAME - xanthosine phosphorylase CITATIONS - :EV-EXP:3277835751:pkarp COMMENT - There are two purine nucleoside phosphorylases in E. coli. /The enzyme coded for by the deoD gene has broader substrate /specificity but cannot act on xanthosine while the one coded for by /the xapA gene is induced by xanthosine,and cannot act on adenine or /the corresponding nucleosides. |CITS: [81122109]| The second /phosphorylase, xanthosine phosphorylase, has been assigned the same /E.C. number as the enzyme coded for by the deoD gene by some /researchers |CITS: [88107903]|. However as xanthosine phosphorylase /acts only on xanthosine the use of the broad substrate E.C. number may /not be correct. ENZYME - XANTHOSINEPHOSPHORY-CPLX REACTION - XANTHOSINEPHOSPHORY-RXN REACTION-DIRECTION - REVERSIBLE REGULATED-BY - REG0-7312 REGULATED-BY - REG0-7311 REGULATED-BY - REG0-7310 REGULATED-BY - REG0-7309 SYNONYMS - purine nucleoside phosphorylase // UNIQUE-ID - XANPRIBOSYLTRAN-ENZRXN TYPES - Enzymatic-Reactions COMMON-NAME - xanthine phosphoribosyltransferase ALTERNATIVE-SUBSTRATES - (XANTHINE HYPOXANTHINE) ALTERNATIVE-SUBSTRATES - (XANTHINE GUANINE) ALTERNATIVE-SUBSTRATES - (XANTHINE GUANINE HYPOXANTHINE) CITATIONS - :EV-EXP:3277835750:pkarp COMMENT - Xanthine-guanine phosphoribosyltransferase is a purine /salvage enzyme which converts either xanthine or guanine to XMP or GMP /respectively. There is evidence that is can also weakly act on /hypoxanthine, although guanine appears to be the preferred substrate. /|CITS: [83238313] [84169518]| ENZYME - GPT-CPLX REACTION - XANPRIBOSYLTRAN-RXN REACTION-DIRECTION - REVERSIBLE REGULATED-BY - REG0-7899 REGULATED-BY - REG0-7898 REGULATED-BY - REG0-7897 SYNONYMS - XGPRT SYNONYMS - xanthine phosphoribosyltransferase SYNONYMS - 5-phospho-α-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase SYNONYMS - guanine phosphoribosyltransferase //